Cell Culture Enthusiast - Organoid and Cell Culture Core
A bit about us: The Organoid and Cell Culture Core (OCCC) generates 2D and 3D in vitro models that can replicate the morphological features of broad epithelial tissues in health and disease. The core offers a range of off-the-shelf frozen organoids and cell lines, as well as supplemental reagents, hands-on training, and expertise to support and guide researchers towards utilizing and/or incorporating organoid and cell culture-based model systems to advance their specific research objectives.
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A bit about you: We are seeking a motivated and talented person with cell culture experience, or a strong desire to learn cell culture, to join the OCCC as a key member of daily operations. Aspiring physician-scientists, surgeon-scientists, and doctoral students are encouraged to apply. Main responsibilities will consist of processing tissues for creating 3D organoid primary cultures and generating, maintaining, and validating a panel of 3D organoids from clinical specimens, xenograft tumors, and genetically engineered mice. You will participate in hands-on training activities and serve as a resource for quality assurance and annotation of organoid and cell culture lines, working closely with the OCCC's technical director to fulfill the scientific objectives of the core, primarily by expanding our library of well-annotated organoid lines. In addition, you may learn to genetically modify 3D organoids (e.g., CRISPR-mediated gene editing), perform high-throughput drug screening of 3D organoids, and develop innovative co-culture systems to model the tumor microenvironment. One of our key goals is to translate 3D organoid technology into personalized medicine. The successful applicant will be considered to participate in these endeavors and undergo training in advanced molecular biology and cell biology techniques.
Responsibilities include:
Minimum Qualifications
Other Requirements
Columbia University is an Equal Opportunity Employer / Disability / Veteran
Pay Transparency Disclosure
The salary of the finalist selected for this role will be set based on a variety of factors, including but not limited to departmental budgets, qualifications, experience, education, licenses, specialty, and training. The above hiring range represents the University's good faith and reasonable estimate of the range of possible compensation at the time of posting.